The universal computer mind Omnius has retreated to its last stronghold, where it plots a devastating new strategy that could undo the victories of the Butlerian Jihad. The surviving Titans are creating new lieutenants to do their will when at last they return to attack the human beings they once ruled.In the years of peace too many of mankind have forgotten that their machine enemies never sleep.But some have forgotten nothing — and learned from their triumphs. The brilliant military commander Vorian Atreides, son of a Titan, has the gift of long life from his terrifying father and knows the machines’ minds better than any man alive. Norma Cenva, the genius inventor of humanity’s best defences, dreams of new discoveries that will make man invincible.And on the windswept desert planet Arrakis, the power that can give them victory waits.

As the no-ship Ithaca flees through space, the heroes of HUNTERS OF DUNE finally meet the Enemy who followed the violent fanatics, the Honored Matres, back to their universe. The thinking machines vanquished by Serena Butler’s jihad were not destroyed, only driven into exile — and now, tens of thousands of years later, they are back. Can the resurrected heroes on board the Ithaca save our race from annihilation?

Fleeing from the monstrous Honored Matres — dark counterparts of the Bene Gesserit Sisterhood — Duncan Idaho, the military genius Bashar Miles Teg, a woman named Sheeana who can talk to sandworms, and a group of desperate refugees explore the boundaries of the universe.Aboard their sophisticated no-ship, they have used long-stored cells to resurrect heroes and villains from the past, including Paul Muad’Dib, in preparation for a final confrontation with a mysterious outside Enemy so great it can destroy even the terrible Honored Matres.And, deep in the hold of their giant ship, the refugees carry the last surviving sandworms from devastated Arrakis, as they search the universe for a new Dune.