The tutorial guide contains information on the diagnosis, differential diagnosis, prevention of tuberculosis and a description of anti-tuberculosis measures for different age periods in primary health care. Diagnostic and therapeutic recommendations are presented in accordance with existing national recommendations, as well as data from scientific domestic and foreign literature.The tutorial guide on the discipline «Phthisiology» has been prepared in accordance with the requirements of the current Federal State Educational Standard of higher education of a specialist in the specialty 31.05.01 «General medicine», 31.05.02 «Pediatrics», 32.05.03 «Preventive medicine», 31.05.03 «Dentistry» and working programs of the disciplines «Phthisiology», «Phthisiopulmonology», «Infectious diseases, Phthisiology» approved by the Central Coordinating Methodological Council of the Federal State Budgetary Educational Institution of the Ministry of Health of Russia.